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Background: Otosclerosis is not an uncommon condition in Telangana. Various methods such as perforator and laser are usedin performing stapedotomy during its surgical management. Stapedotomy performed with slow-speed microdrill technique forotosclerosis, and difficulties encountered during surgery, complications, and auditory gain in the post-operative period wereanalyzed in this study.Aim of the Study: The aim of this study was to use low-speed microdrill technique in stapedotomy and to analyze the difficulties,complications, and audiological evaluation in the post-operative period of 18 months.Materials and Methods: A prospective study of 62 patients undergoing stapedotomy for otosclerosis over a period of 2 yearswas reviewed. Stapedotomy with skeeter microdrill was evaluated using audiometric results (air conduction thresholds, boneconduction thresholds, air-bone gap closure, and pure tone average) and the incidence of complications during post-operativeperiod. Teflon prosthesis was used in all the patients.Observations and Results: Among the 62 patients, there were 37 females (59.67%) and 25 males (40.32%) with a male-tofemale ratio of 1:1.48. The patients belonged to the age group of 25–55 years with a mean age of 32.65 ± 4.15 years.Conclusions: Stapedotomy performed with microdrill technique for otosclerosis was a safe surgical technique to perforate thestapes footplate. The microdrill (skeeter) has low noise intensity and low torque. For duration of a few seconds, it seems to bea safe tool in creating a perforation in the footplate of the stapes, without causing acoustic trauma.
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Background: Self-medication is widely practiced worldwide and often considered as a component of self-care. Selfmedication assumes a special significance among the medical students as they are the future medical practitioners and have a potential role in counselling the patients about the advantages and disadvantages of self-medication. Self-medication assumes a special significance among the medical students as they are the future medical practitioners. Medical students also differ from the general population because they are well-exposed to the knowledge about diseases and drugs. Therefore the present study was taken up to assess the extent of knowledge and practices of over the counter (OTC) drugs among the first year medical students in a tertiary care teaching hospital.Methods: A descriptive, cross sectional, non-interventional, observational study was conducted from November 2017 to January 2018 among 246 first year medical students. The data analyzed using descriptive statistics with percentages and averages using Statistical Package for Social Science (SPSS).Results: In the present study, it was found that 86% students practiced self-medication. Most common conditions for taking self-medication with OTC was fever (89%) followed by cough and cold (75%). 15% of them experienced adverse reactions on OTC self-medicated drugs. The main source of information during self-medication was reading material (56.3%) followed by advice from seniors/pharmacist (43.7%).Conclusions: Self-medication is widely practiced among undergraduate medical students. In this situation, we should educate the students about advantages and disadvantages of self-medication of over the counter drugs.
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Background: Dengue fever is a mosquito borne viral infection which has become a global health hazard, especially in tropical and subtropical areas. Children have higher risk of developing severe forms of dengue fever, however, studies show that paediatric complications/fatalities from dengue fever are potentially avoidable by proper management. Data about drug usage patterns for dengue are particularly lacking, especially in the paediatric age group, therefore this study will help facilitate the rational use of drugs and aid in establishing a more specific management for dengue fever. The objective of the present study was to identify the prescribing pattern of dengue fever in paediatric inpatients admitted to RajaRajeswari Medical College and Hospital and assess according to the WHO core prescribing indicatorsMethods: This prospective observational study took place from March 2017 to September 2017 in the paediatric general wards. Data was collected from case files of NS1 positive patients of both genders between 1-18years. Data was analysed using descriptive statistics and expressed as percentages, means and standard deviations. The prescription pattern was analysed using the prescribing indicators mentioned in the World Health Organization core drug use indicators.Results: Total of 300 drugs were prescribed for 110 prescriptions that were analysed excluding IV fluids and blood products. Mean number of drugs prescribed was 2.7±0.8. Drugs prescribed by a generic name was 7.33%. Patients prescribed an antibiotic was 12.73%. Patients prescribed with an injection was 62.72% Majority of drugs prescribed in this study come from essential medicines list created by regulatory bodies. Intravenous fluids were administered to all patients with majority receiving normal saline (60.9%).Conclusions: Mainstay of treatment of dengue fever for paediatric patients is symptomatic along with focus on fluid management. Majority of drugs prescribed are from essential medicines lists formed by regulatory bodies. With dengue infections being a worldwide health hazard, more studies are needed to facilitate rational use of drugs in this disease.
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Background: Surgery on the ocular tissue brings about activation of phospholipase A3 thereby releasing prostaglandins and leukotrienes. Prostaglandins bring about meiosis during surgery, changes in IOP, conjunctival hyperaemia. Newer topical NSAID抯 Nepafenac and Flurbiprofen are potent inhibitors of the cyclooxygenase enzyme thereby inhibiting the biosynthesis of prostaglandins. Objective of this study was to compare the efficacy of preoperative use of topical Nepafenac (0.1%) and Flurbiprofen (0.03%) in maintenance of intraoperative mydriasis during cataract surgery.Methods: A randomised, comparative study was performed on 104 patients, 52 were allocated in each group and were given either of the topical NSAID抯 Nepafenac or Flurbiprofen prior to cataract surgery. Pupillary diameter was measured at the beginning and at the end of the surgery and the values were compared between the groups. Mean and standard deviation was calculated and between two groups comparison was done using students t-test.Results: The mean pupillary diameter of the two groups were comparable at the beginning of surgery (p=0.34). The mean change in the pupillary diameter was 1.86�71mm in the Nepafenac group and 1.77�72mm in the Flurbiprofen group. There was no statistically significant difference among both the groups in maintenance of intraoperative mydriasis (p=0.47).Conclusions: Pre-operative use of Nepafenac and Flurbiprofen were equally effective in preventing meiosis during cataract surgery.
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Background: Patella is the largest sesamoid bone in the body situated in the quadriceps tendon1. The main function of patella is to improve the efficiency of quadriceps muscle by improving the mechanical leverage of the quadriceps muscle. Patellar fractures are common and it constitutes about 1% of all skeletal injuries resulting from either direct or indirect trauma2.The subcutaneous location of the patella makes it vulnerable to direct trauma.Aims of the study were to evaluate the clinical outcome of Transverse fractures of patella treated with modified tension band wiring. The objectives of the study are to study the advantages of modified tension band wiring fixation in patellar fracture, the complications associated with this method of fixation and to assess the role of early mobilization with this technique. Methods: This prospective study is done in Department of Orthopaedics at R L Jalappa Hospital and Research Center, attached to Sri DevarajUrs Medical College, Kolarduring the period from December 2010 to June 2012. This study consists of 30 cases of displaced transverse fracture patella treated by modified tension band wiring. The cases were selected based on inclusion and exclusion criteria. After pre anaesthetic fitness patient, patient was operated (tension band wiring). Operatedknee was immobilized in extension in an above knee posterior slab, and advised to do straight leg raising test.Weight bearing was started from 3rd post-operative day. Sutures were removed on 12th to 14thpost operative day. The discharged patients were advised to report for follow up every month, during each follow up the patients were examined for both subjective symptoms and objective signs which was recorded. The patients were questioned about subjective complaints like pain, difficulty in walking, squatting, climbing and getting down stairs and ability to perform routine work. The patient’s objective assessment was done for Extensor lag, Range of knee movement, circumference of thigh (wasting) and Efficacy of quadriceps (power).Results: The range of age of fracture of patella in our series was between 19-70 years, the mean age was 42 years and the incidence was high in the age group of 31-40 years. In a total of 30 cases, 24 fractures were in men and 6 fractures were in females.22 fractures were as a result of indirect mechanism and 8 cases were due to direct trauma to the patella as in RTA. 17 patients had fracture on the right side and 13 patients had fracture on the left side.Average duration between injuries to hospital admission was about 1.16 days. The average duration between the days of admission to the day of surgery is about 2.93 days and the average duration of stay in hospital is about 13.2 days (ranging from 11 to 22 days).No intra operative complications like fragmentation at wiring, difficulty in closure were encountered. Results were excellent in 26 cases, good in 3 cases and bad in 1 caseasper west’s criteria. Conclusion: Thus we conclude that anatomical reduction and stable fixation in patellar fracture is necessary for the normal integrity and stability of the joint.Early post-operative physiotherapy plays an important role in final outcome, which helps in reducing complication like stiffness of knee and in providing good functional. Our outcome was not influenced by the associated injuries. Long-term follow up is necessary to assess late complications like osteoarthritis and late functional outcome.
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Thirty genotypes of kabuli chickpea were used to study the extent of genetic variability, correlation and path analysis for yield and yield contributing characters. Wider genetic variability with high heritability and high genetic advance as per cent of mean was recorded for number of primary branches per plant, biological yield per plant and seed yield per plant. Correlation studies revealed that seed yield was significantly and positively correlated with plant height, number of primary branches per plant, number of secondary branches per plant, number of pods per plant, 100-seed weight, harvest index and biological yield per plant. Path coefficient analysis indicated that biological yield per plant, number of pods per plant and harvest index had high positive direct effect on seed yield signifying the importance of these traits in improvement of seed yield.